your mobos have eSATA ports;
and the BIOS supports booting from them;
and the BIOS supports reordering the boot devices;
and Fedora understands the sata chips on the mobos;
...you might be just fine for a desktop.
Without eSATA you have to start looking at bootable DVDs, flash devices, or external USB, which are ok for trials, testing, or embedded things but a bit slow and frustrating for everyday desktop use.
You can download bootable fedora live desktop dvd's from the FedoraProject, if you didn't know.