They are deactivated b/c you configure them to use NetworkManager(NM). It's not obvious but either NM or 'network' service has control of each interface - not both. These tools try weakly to not interfere w/ each other.
They have merged some of the config info but it's kind of a hack IMO. Work in progress.
Altho' there is work underway to improve NM, IMO you should still use 'netwprk' to configure most wired interfaces. It's definitely a joy to use for wireless.
None are more hopelessly enslaved than those who falsely believe they are free.
Johann Wolfgang von Goethe