Actually with the new skype, that isn't necessary--doing yum install (not even local install) to the downloaded rpm should provide all needed 32 bit libs--it has for me and a few other people on the forums.
Seems like it might be Skype rather than Fedora this time, if the mike is working on all other programs.
There's one old solution, might be completely irrelevant now, but helped me in the past.
Post number 9 in the thread.
Edit--I see that in another similar thread, that Ubuntu thread didn't help Zoroid, so I don't hold out much hope for it.