I'm running FC 14 on an Alienware m15x-R1. It's an older one that they made before Dell bought them out.
My problem is that the internal speakers don't work, but if I plug a headset in to the audio jack, it works fine.
lspci tells me I have an audio device Intel Corp HD Audio Controller, which may or may not be helpful. I booted it up with an Ubuntu live CD just to make sure it was the hardware, and I get the same results.